akers misplaced their footing after Pfizer's COVID-19 antiviral tablet confirmed promising efficacy in a trial. Promoted Hyperlinks If You Purchased $1,000 Price of Litecoin 3 Years In the past, Here is How A lot You'd Have Immediately Anti-Growing older Merchandise In Pakistan Might Be Turning Heads Anti Growing older | Search Advertisements 3 Electrical Automobile Charging Station Shares for 2021 Elon Musk, again on Twitter, turns his assist to Dogecoin TOKYO, Nov 8 (Reuters) - Japanese shares closed decrease on Monday as development shares weakened on some downbeat earnings, whereas drugmakers misplaced their footing after Pfizer's COVID-19 antiviral tablet confirmed promising efficacy in a trial. The Nikkei share common .N225 fell 0.35% to 29,507.05, regardless of Wall Road ending robust on Friday, slipping from a one-month excessive hit on Thursday. The broader Topix .TOPX ended 0.30% decrease at 2,035.22. With Japanese company earnings season in full swing this week, buyers have been hesitant to purchase close to the Nikkei's psychological resistance at 30,000. Obayashi Corp 1802.T dropped 9.2% after the builder slashed its steerage sharply, hit partially by rising prices, whereas rival Shimizu Corp 1803.T shed 7.7% on disappointing earnings. Consequently, the development sector .ICONS.T fell 1.9%. Drugmaker Shionogi 4507.T misplaced 5.7% and Chugai Pharmaceutical 4519.T declined 3.7% after rival Pfizer PFE.N stated its experimental tablet reduce by 89% the prospect of hospitalization or demise from COVID-19. Mixi 2121.T sank by its day by day restrict, shedding 18.2% after the web agency reduce its earnings steerage sharply on poor gross sales of its major sport service. However, endoscope maker Olympus 7733.T jumped 6.0% on bumper earnings outcomes, whereas Sega Sammy 6460.T rose 7.8% after the sport firm reported robust earnings and introduced a share buyback. Whole internet earnings from Japanese firms which have to this point introduced outcomes have crushed consensus estimates, on common, by 12%, stated Nobuhiko Kuramochi, market strategist at Mizuho Securities. "However general they are not that spectacular. And ahead earnings expectations have been virtually flat prior to now month," he stated. exp-player-logo transition-logo Airways .IAIRL.T and prepare operators .IRAIL.T gained on information of Pfizer's COVID-19 drug, because it added to hopes of financial restoration amid a fall in infections at house. Greater than 1,500 firms are scheduled to announce quarterly outcomes this week, together with SoftBank Group 9984.T on Monday, Nissan Motor 7201.T on Tuesday and Tokyo Electron 8035.T on Friday. (Reporting by Hideyuki Sano; Enhancing by Rashmi Aich and Ramakrishnan M.) ((hideyuki.sano@thomsonreuters.com; +81 3 4520 1195;)) The views and opinions expressed herein are the views and opinions of the writer and don't essentially replicate these of Nasdaq, Inc.

Hong Kong stocks declined for a second day with tech firms leading losers as the Chinese Communist Party kicked off a key meeting in Beijing under a cloud of economic slowdown.

The Hang Seng Index retreated 0.4 per cent to 24,763.77 at the close of Monday trading. The Hang Seng Tech Index slid 1.3 per cent, while China‘s Shanghai Composite Index added 0.2 per cent.

Alibaba Group Holding, the owner of this newspaper, sank 1.6 per cent, while its health unit lost 1.2 per cent. Meituan tumbled 2 per cent, while Tencent Holdings retreated 0.8 per cent. Analysts have trimmed their price targets on the trio by 18 to 25 per cent over the past six months following a regulatory crackdown on their businesses.

President Xi Jinping, who is also general secretary of the party, will open the sixth plenary session of the 19th Central Committee on Monday. Investors will be evaluating a new resolution on the party’s “major achievements and historical experience,” which is expected to be adopted at a political gathering, for clues on policies.

After chalking up a 3.3 per cent gain in October, the Hang Seng Index has since given up 2.4 per cent this month. They retreated even as exports grew last month at a faster pace than economists predicted, while imports trailed estimates. The spread of Delta variant in many provinces have led to stricter lockdowns, weighing on economic recovery efforts.

“ While we still expect more stimulus from China, it has been less forthcoming than we originally expected, with policymakers prioritising deleveraging over short-term growth,” Pictet Asset Management said in its latest market outlook report. “A renewed surge in Covid cases in China is also a cause for concern.”

Biotechnology stocks retreated, as Pfizer released data that its Covid-19 pill could reduce hospitalisations and deaths in high-risk patients. WuXi Biologics was the index‘s biggest loser as it plunged 8.6 per cent, while Sino Biopharmaceutical declined 1.6 percent.

Major markets in Asia retreated. Stock benchmarks in South Korea and Japan lost about 0.3 per cent, while the Australian index was little changed.

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